Open Access

Synthesis of Mercapto Heterocyclic Derivatives of 1-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-thio-propan-1-one and its Biological Activities

Venugopal Sivasankaranan, drdsaro@gmail.com
Department of Chemistry, National College, Tiruchirappalli, TN, India. Dhandayutham Saravanan, drdsaro@gmail.com
Department of Chemistry, National College, Tiruchirappalli, TN, India. Manivachagam Chandrasekaran, drdsaro@gmail.com
Department of Botany, Annamalai University, Annamalainagar, TN, India. Gnanaprakasam Adaikalaraj drdsaro@gmail.com
Department of Botany, Annamalai University, Annamalainagar, TN, India.

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Abstract

In the present study, a new series of mercapto heterocyclic derivatives of 1-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-thio-propan-1-one derivatives are synthesized. The chemical structures were confirmed by IR, 1H-NMR and mass spectral analysis. The compounds were screened for antibacterial and antifungal activity. It shows good antibacterial and antifungal activity for most of synthesized compounds.

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