Open Access

Synthesis, Spectral Characterization and Biological Study of 3-of 3- Chloro-2,6-Bis-(4-Methoxy-Phenyl)-3-Methyl-Piperidin-4-One

M. Seeni Mubarak, Department of Chemistry, Jamal Mohamed College (Autonomous), Tiruchirappalli, TN, India. M. I. Fazal Mohamed, Department of Chemistry, Jamal Mohamed College (Autonomous), Tiruchirappalli, TN, India. M. Sathya Narayanan*, sathyachem07@gmail.com
Department of Chemistry, Jamal Mohamed College (Autonomous), Tiruchirappalli, TN, India.
R. Kathirvel, Department of Chemistry, Jamal Mohamed College (Autonomous), Tiruchirappalli, TN, India. S. Mohamed Rabeek Department of Chemistry, Jamal Mohamed College (Autonomous), Tiruchirappalli, TN, India.


J. Environ. Nanotechnol., Volume 3, No 4 (2014) pp. 13-15

https://doi.org/10.13074/jent.2014.12.143093

PDF


Abstract

Piperidin is an important class of heterocyclic compound which forms a part in many of the alkaloid compounds. Such compounds play a vital role in the field of medicinal chemistry. Several 2, 6-disubstituted derivatives of piperidin compounds are found to posses biological activities such as herbicidal, fungicidal, anticancer, anesthetic etc. In the present work a new piperidin -4-one with chloro and methyl substitution at 3-position have been prepared and characterized using IR,1 H NMR, 13C NMR and Biological studies.

Full Text

Reference


Agarwal, O. P., Chemistry of Organic Natural Product, Goel Publishing House Meerat., 1(2002).

Baliah, V., Ekamabaram, A., Govindarajan, T. S., Condensation of Acetone with aldehydes and ammonia, Curr. Sci., 23, 264(1954).

Noller, C., Baliah, V., The Preparation of Some Piperidine Derivatives by the Mannich Reaction, J. Am. Chem. Soc., 70(11), 3853-3855 (1948).

doi:10.1021/ja01191a092

Silverstein, Bessler and Morill, Spectroscopic Identification of Organic Compounds, 4th
Edition, Wiley, (1981).

Contact Us

Powered by

Powered by OJS