Green Synthesis, Characterization and Medicinal Applications of Zinc Oxide Nanoparticles
J. Environ. Nanotechnol., Volume 14, No 1 (2025) pp. 137-143
Abstract
In this study, zinc oxide nanoparticles (ZnO NPs) were green synthesized using the leaves of Cardaria draba, their properties have been thoroughly investigated and their antibacterial and anticancer activities were assessed. X-ray diffraction (XRD) revealed the crystalline structure and the phase purity of ZnO nanocrystals with an average crystal size of 30 nm. UV-visible spectroscopic analysis indicated the occurrence of an absorption band at 310 nm attributed to the phenomenon of Surface Plasmon Resonance (SPR). FTIR spectroscopic analysis was employed to study the functional groups present in the nanoparticles. Additionally, microscopic characterization of ZnO NPs was performed using AFM, DLS and SEM with EDEX. The ZnO NPs showed an inhibition zone of 26 mm against S. aureus and 19 mm against E. coli at 100 µg/mL. The green synthesized zinc oxide nanoparticles exhibited good anti-cancer activity against MCF-7 breast cancer cells.
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